smoking facts

Varenicline
- Champix and Chantix as Stop Smoking Medications

Varenicline tartrate is the chemical in the stop smoking medications sold as Champix and Chantix.

Using chemicals to support a nicotine withdrawal needs serious consideration in the overall treatment decision to help stop smoking. Medications can have psychotropic effects, and these ones have been shown to have some serious side effects that can affect your mental health.

Balance the harmful effects of smoking cigarettes against the serious side effects of these stop smoking drugs.

Champix (Canada) and Chantix (USA)
Neuropsychiatric Drug Warnings

These stop smoking drugs are reported to reduce nicotine withdrawal symptoms, especially cravings.

There is some evidence that the drug reduces the "pleasure" sensation in the smoker's brain so that the nicotine hit is not as pleasurable.

In order to accomplish this action the drug must work on brain chemistry and neurotransmitters so it is not surprising that some neuropsychiatric side effects of these stop smoking medications have now been identified.

In 2008 Pfizer, the company that markets varenicline notified authorities of serious post marketing neuropsychiatric adverse events.

These are specified to be:

  • hostility
  • agitation
  • depressed mood
  • suicidal thoughts

In 2008 the FDA in the United States issued a warning to consumers regarding Chantix. Health Canada followed with a similar warning in 2009 about Champix. Both warnings indicated that there may be an association between varenicline and "serious neuropsychiatric symptoms."

The drug monographs included with the medication were subsequently modified to include this new information and the drugs remain legally available by prescription in both countries.

Many people have had success using these stop smoking medications without any hint of the serious side effects issued in Pfizer's warning. However, the warning is there because some people have been adversely affected by the use of these prescription drugs.

Your decision to use a drug that affects the brain neuro-chemistry should be made based on thorough investigation of the risks and benefits, assessment of your own needs, knowledge of your own response to medications and drugs, and of course consultation with a health care professional qualified to assist you with the quit smoking decision.


Other stop smoking pills include Zyban which is chemical the same as the antidepressant sold as Wellbutrin.

The generic name for this stop smoking medication is buproprion.

There is no such thing as a risk free drug.

Some serious buproprion side effects have been reported. Make sure you know about the side effects of Wellbutrin or Zyban as stop smoking drugs.

An Explanation of How Zyban Works

Inform yourself about any prescription drug that you might take.

Go from this explanation of
Varenicline Tartrate - Champix and Chantix as Stop Smoking Medications to Prescription Drugs and Side Effects


Go back to Stop Smoking Pills - Using Chantix and the Drug Zyban
to Control Nicotine Withdrawal Symptoms

Return to the Home Page: Smoking Facts Reveal
The Real Dangers of Cigarette Smoking


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